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Cannabigerolic Acid (CBGA)

Cannabigerolic acid (CBGA) is a minor cannaboid out of the many and numerous cannabinoids from the marijuana plant. CBGA is produced from the trichomes in the cannabis plant and allows for natural leaf pruning. This will give the plant the ability to avail its resources toward the flower.

Some might refer to CBGA as the grandfather of cannabinoids because it is at the top of the chain of the three different cannabinoid lines, being tetrahydrocannabinolic acid, cannabidiolic acid, and cannabichromenic acid. Sometimes, CBGA converts into CBG, but in most strains it will convert into CBD or THC. There hasn’t been a huge amount of research that has actually been conducted on CBGA, but scientists have dated it back to about 50 years ago when Israeli scientists found a way to isolate cannabigerol (CBG). It was around 30 years later that Japanese scientists determined the CBGA was the precursor to CBG.

Even though there hasn’t been much credible research, some studies point to the fact that it will have future uses. CBGA may assist in some of the negative symptoms of diabetes such as cardiovascular disease. One research group found that CBGA can help people deal with some of the related issues from metabolic disorders and may reduce lipid accumulation that may lead to higher levels of cholesterol. Studies still need to be done with animal and human trials to further validate this research. One specific study found that CBGA may one day be very important for people with colorectal cancer.

Researchers realized the cytotoxic effects of CBGA that was extracted from marijuana, and were shocked to find it having killed the colon cancer cells. Even though further research is required on this, it showed early promise that CBGA can potentially be effective at preventing these cancer cells from turning into polyps.

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